Product Description
Ketoadd Tablet serves as a vital supplement in chronic renal insufficiency, providing essential amino acids and ketoanalogues to optimize protein synthesis while minimizing uremic toxins. Patients with diabetic nephropathy or non-dialysis CKD benefit from its role in preventing hyperuremia, maintaining lean body mass, and supporting metabolic balance during low-protein diets (0.6-0.8 g/kg/day). Clinical studies show alpha-ketoanalogues reduce serum creatinine, boost hemoglobin, and improve estimated glomerular filtration rate (eGFR), potentially postponing dialysis needs.
Key benefits include:
- Lowers blood urea nitrogen (BUN) and proteinuria in predialysis CKD
- Supplies calcium to counter hypocalcemia risks in renal failure.
- Improves lipid profiles and reduces uremic symptoms like fatigue and nausea.Administer 1 tablet three times daily with meals under medical supervision; monitor calcium levels to avoid hypercalcemia. Not for keto diet weight loss—strictly for renal health management
Key Ingredients
Each tablet typically includes:
Alpha-ketoanalogues (381 mg total): Calcium salts of keto-leucine (101 mg), keto-isoleucine (67 mg), keto-valine (86 mg), keto-phenylalanine (68 mg), and hydroxy-methionine (59 mg).
Essential amino acids: L-histidine (38 mg), L-lysine acetate (105 mg), L-threonine (53 mg), L-tryptophan (23 mg), L-tyrosine (30 mg).
Mechanism of Action
Alpha-ketoanalogues transaminate with endogenous amino acids in muscles and organs, forming essential amino acids for protein synthesis while generating minimal waste like urea or ammonia. This lowers blood urea nitrogen (BUN), serum creatinine, and proteinuria in CKD patients on low-protein diets (0.6-0.8 g/kg/day). The added amino acids and calcium address deficiencies, prevent hypocalcemia, improve glomerular filtration rate (eGFR), and delay dialysis progression by reducing uremic toxins and preserving nutritional status. Overall, it optimizes nitrogen balance, slows CKD advancement, and alleviates symptoms like fatigue.
